NCT06465407

Collagen Protein Versus Placebo on Muscle Recovery

Effect of Collagen Protein Versus Placebo on Indirect Markers of Musculotendinous Unit Recovery Following Eccentric Plantar Flexor Exercise

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (estimated)
• Sponsor: University of Central Florida · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

This study is focused on exploring the gap in the literature by comparing the effects of collagen protein versus placebo supplementation on the musculotendinous unit following muscle damaging protocol. Thus, the purpose of this study is to identify and compare the effect of collagen protein versus placebo supplementation on indirect markers of musculotendinous unit recovery following eccentric calf exercises.

Detailed description

Various physical assessments that include pain scale, pain pressure threshold assessment, body composition, calf circumference measurements, muscle thickness measurements, Achilles tendon length and thickness measurements, myotonography of the calf, isometric force assessments during standing and seated plantarflexion positions, a heel raise test, and a standardized exercise routine focused on eccentric movements, targeting a leg chosen at random. Additionally, will consume a daily dose of two 30-g amount of collagen peptides derived from bovine hide (commercially available as Vital Proteins or Peptan) or placebo (30 g of pure maltodextrin with no amino acids) mixed in 300 ml of orange Gatorade zero. Gatorade zero, maltodextrin, and collagen is going to be stored in the locked cabinet in the lab. Research team will mix the supplement (placebo or maltodextrin) with Gatorade zero in a non-clear bottle and will administer it to the participants on-site.

Conditions

• Anthropometrics: Height and Weight
• Isometric Standing and Seated Plantarflexion
• Calf Muscle Thickness
• Achilles Tendon Length and Thickness
• Myotonography of the Calf Musculature and Achilles Tendon
• Pain Pressure Threshold of the Calf
• Pain Scale
• Endurance Calf Test
• Dietary Analysis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Collagen	Participants will consume two 30-g amount of collagen peptides derived from bovine hide (commercially available as Vital Proteins or Peptan) mixed in 300 ml of orange gatorade zero.
DIETARY_SUPPLEMENT	Maltodextrin	Participants will consume two 30-g amount of pure maltodextrin mixed in 300 ml of orange gatorade zero.

Timeline

• Start date: 2024-07-01
• Primary completion: 2024-10-30
• Completion: 2024-12-01
• First posted: 2024-06-18
• Last updated: 2024-06-18

Locations

1 site across 1 country: United States