NCT06464770

Optimizing Infection Prophylaxis Prior to Shoulder Surgery

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Washington · Academic / Other
• Sex: Male
• Age: 18 Years – 89 Years
• Healthy volunteers: Accepted

Summary

The goal of this interventional study is to determine the amount of skin C. acnes reduction with increased pressure during the chlorhexidine gluconate, brand name ChloraPrep, application. The main question it aims to answer is: Does changing the pressure applied during the ChloraPrep application impact the amount of C. acnes bacteria on the skin after one hour? Researchers will compare ChloraPrep applied at a pressure similar to a gentle wipe to ChloraPrep applied at a pressure similar to a massage to see if wash the amount of C. acnes on the skin after one hour is different. Participants will have one shoulder washed with ChloraPrep using pressure meant to impact the dermal layer, similar to a gentle wipe, and the other shoulder washed with ChloraPrep using pressure meant to impact the subdermal layer, similar to a massage. Participants will have swabs taken of their skin before the ChloraPrep application and again one hour after application to look for the amount of C. acnes on the skin.

Conditions

• Arthroplasty Shoulder
• Periprosthetic Joint Infection

Interventions

Type	Name	Description
DRUG	Chlorhexidine Gluconate	Test Group: the participant's shoulder skin will be treated by the study team with the standard chlorhexidine wash at lower pressure (similar to a gentle wipe) for 30 seconds Control Group: the participant's shoulder skin will be treated by the study team with the standard chlorhexidine wash at higher pressure (similar to a massage) for 30 seconds

Timeline

• Start date: 2024-08-31
• Primary completion: 2026-12-31
• Completion: 2027-12-31
• First posted: 2024-06-18
• Last updated: 2024-12-05

Locations

1 site across 1 country: United States