Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06459973

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

A Multi-center, Open-label, Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of YL205 in Patients With Advanced Solid Tumors

Status
Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
252 (estimated)
Sponsor
MediLink Therapeutics (Suzhou) Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a multicenter, open-label, phase I/II study of YL205 in China to evaluate the safety, tolerability, PK characteristics and preliminary efficacy of YL205 in the following selected patients with advanced solid tumors.

Conditions

Interventions

TypeNameDescription
DRUGintravenous (IV) infusionYL205 is provided in the form of lyophilized powder under a strength of 160 mg/vial. Each vial should be reconstituted to 20 mg/mL. Prior to IV infusionSubjects will be treated with YL205 via intravenous (IV) infusion, once every 3 weeks (Q3W) as a treatment cycle

Timeline

Start date
2024-06-04
Primary completion
2027-07-31
Completion
2030-07-31
First posted
2024-06-14
Last updated
2025-12-23

Locations

43 sites across 2 countries: United States, China

Regulatory

Source: ClinicalTrials.gov record NCT06459973. Inclusion in this directory is not an endorsement.