Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT06459921

Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer

Efficacy and Safety of Neoadjuvant Sintilimab Puls FLOT Versus Sintilimab Puls SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Xijing Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This study aims to investigate the efficacy and safety of Sintilimab combined with FOLT versus Sintilimab combined with SOX in patients with locally advanced gastric cancer. The research design is intended to observe the comparison of conversion therapy effects, disease-free survival, R0 resection rate, and safety evaluation between the two groups.

Conditions

Interventions

TypeNameDescription
DRUGSOX+SintilimabPatients would be allocated to the SOX+Sintilimab group.
DRUGFLOT+SintilimabPatients would be allocated to the FLOT+Sintilimab group.

Timeline

Start date
2024-12-01
Primary completion
2026-07-01
Completion
2028-12-31
First posted
2024-06-14
Last updated
2024-10-10

Source: ClinicalTrials.gov record NCT06459921. Inclusion in this directory is not an endorsement.