NCT06451471

"Galectin-3 as a Marker of Subclinical Inflammation in FMF"

Assessment of Serum Galectin-3 Level as an Indicator of Subclinical Inflammation in Patients With Familial Mediterranean Fever

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 154 (actual)
• Sponsor: Turkish League Against Rheumatism · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to learn about the relationship between serum Galectin-3 levels and subclinical inflammation in patients with Familial Mediterranean Fever (FMF). The main questions it aims to answer are: * Are serum Galectin-3 levels higher in FMF patients compared to healthy controls? * Is there a positive correlation between serum Galectin-3 levels and Serum Amyloid A (SAA) protein levels in FMF patients? Participants will: * Provide blood samples to measure serum Galectin-3 and SAA levels. * Complete a sociodemographic and clinical data form. * Fill out the FMF Quality of Life (QoL) scale. Researchers will compare FMF patients and healthy controls to see if there are significant differences in serum Galectin-3 levels and to determine the correlation between Galectin-3 and SAA protein levels in FMF patients.

Conditions

• Ailesel Akdeniz Ateşi

Timeline

• Start date: 2021-05-01
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2024-06-11
• Last updated: 2024-06-11

Locations

1 site across 1 country: Turkey (Türkiye)