NCT06450353

Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,200 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).

Detailed description

Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC. Secondary Objectives * To prospectively evaluate time to transplant for allograft candidates at MDACC. * To evaluate treatment-related mortality for allograft candidates at MDACC. * To assess overall survival for allograft candidates at MDACC. * To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC. * To evaluate receipt of an optimal graft for allograft recipients at MDACC.

Conditions

• Allogeneic Transplantation

Interventions

Type	Name	Description
BEHAVIORAL	Patient Ancestry Questionnaires	Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.

Timeline

• Start date: 2024-05-31
• Primary completion: 2027-06-01
• Completion: 2029-06-01
• First posted: 2024-06-10
• Last updated: 2026-01-14

Locations

1 site across 1 country: United States