NCT06448858

Minerals Status in Relation to Overweight and Obese Adolescent

Effect of Body Composition on Some Blood Minerals Status in Obese and Overweight Adolescent; Cross Sectional Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 84 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: —

Summary

Evaluation of the concentration of serum Mn, Se, iron, Cu \& Zn levels in obese and overweight adolescents, Correlate the body composition parameters with these minerals' concentration, Study the association between the metabolic risk factors and the disturbance in minerals levels in these patients.

Detailed description

Obesity in the population tends to be a notable public health threat on the global scale . individuals with higher body mass index (BMI) are considered to have a lower life expectancy . Among the obesity-related indicators, visceral adipose tissue (VAT) is acknowledged an emerging and sensitive predictor for the risk of metabolic syndrome and cardiovascular disease . Therefore, adverse VAT accumulation can influence metabolic health in the population, and its related risk factors should be further investigated. Micronutrients in obese people are explored because of an excess energy consumption, and therefore, an inadequate intake of trace elements and minerals. This imbalance among energy consumption and the intake is known as hidden hunger. Obesity can lead to nutritional metabolic disorders, in which the general state of trace elements and minerals are altered. Only a few studies on child and adolescents obesity concerned Trace Elements (TE). TE is involved in the pathogenesis of obesity and obesity related diseases. We tried to assess trace elements status \[ Manganese (Mn), selenium (Se) copper (Cu),zinc (Zn)\] in obese children and their relationships with VAT and metabolic risk factors of obesity. Manganese (Mn) is an essential trace element . It plays an important role in fat metabolism. Selenium (Se) is an essential micronutrient that acts as an antioxidant and possesses multiple metabolic properties. Copper (Cu) is a trace element that is vital. Cu has been reported to play a role in fat metabolism. Zinc (Zn) plays an important role. Its deficiency impairs growth, metabolism and immunity. Iron (Fe) is an essential trace element to sustain all forms of life. Existing research indicates iron deficiency is one of the comorbidities associated with obesity .

Conditions

• Mineral Deficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum Mn, Se, iron, Cu & Zn levels	Evaluate the concentration of serum Mn, Se, iron, Cu \& Zn levels in obese and overweight adolescents.

Timeline

• Start date: 2024-06-01
• Primary completion: 2025-05-01
• Completion: 2025-06-01
• First posted: 2024-06-07
• Last updated: 2024-06-07

Locations

1 site across 1 country: Egypt