Trials / Recruiting
RecruitingNCT06447714
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
A Prospective Cohort Study on the Correlation Between Patient Cotinine Levels and Intracranial Unruptured Aneurysm Wall Enhancement Based on High-resolution Magnetic Resonance Imaging
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 450 (estimated)
- Sponsor
- Zhujiang Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing. The enrolled patients underwent high-resolution magnetic resonance angiography to detect whether the intracranial aneurysm wall was enhanced and classify the degree of enhancement. The purpose is to study the correlation between arterial aneurysm wall enhancement and cotinine levels
Detailed description
This study aims to explore the relationship between cotinine levels and the risk of intracranial aneurysm rupture by collecting imaging features and patient cotinine levels of unruptured intracranial aneurysms on high-resolution magnetic resonance imaging, combined with the prognosis of patients with aneurysms. Previous studies have shown that the risk of intracranial aneurysm rupture in patients is related to the enhancement of the aneurysm wall on high-resolution magnetic resonance imaging. Therefore, this study included patients who met the inclusion criteria for high-resolution magnetic resonance imaging and cotinine testing, and followed up on the imaging characteristics, prognostic scores, and aneurysm occlusion rate of arterial aneurysms in patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | smoke | cotinine detection |
Timeline
- Start date
- 2022-09-01
- Primary completion
- 2027-03-01
- Completion
- 2027-03-01
- First posted
- 2024-06-07
- Last updated
- 2025-07-18
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06447714. Inclusion in this directory is not an endorsement.