NCT06447675

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder: A Single-center, Self Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Xuanwu Hospital, Beijing · Academic / Other
• Sex: All
• Age: 6 Months – 6 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this research is to study the efficacy and safety of hyperthermic baths as adjunctive therapy for reducing the frequency of seizures in CDKL5 deficiency.

Detailed description

This project aims to include 8 participants, and evaluate the effectiveness and safety of hyperthermic baths in patients with CDKL5 deficiency through A single-center, preliminary feasibility clinical trial. It is expected to provide new therapeutic options for patients with CDKL5 deficiency with alternative treatment options.

Conditions

• CDKL5 Deficiency Disorder

Interventions

Type	Name	Description
OTHER	Hyperthermic Baths	The intervention will consist of 12 weeks of repeated, daily 20-min body immersions.

Timeline

• Start date: 2024-09-20
• Primary completion: 2025-06-25
• Completion: 2025-09-30
• First posted: 2024-06-07
• Last updated: 2026-04-15

Locations

1 site across 1 country: China