NCT06447038

Pilot Study for the Early Detection of Chronic Kidney Disease, Non-Dialysis Objective (NDO).

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: Hospital Universitario de Burgos · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Chronic kidney disease (CKD) is a significant public health problem worldwide, affecting more than 10% of the Spanish population. Early detection is considered a top healthcare priority to establish strategies for preventing progression to more advanced stages of the disease and its complications. Additionally, CKD is associated with high comorbidity, poor prognosis, and substantial resource consumption within the healthcare system. In this context, albuminuria may be a more sensitive marker of CKD than reduced glomerular filtration rate (GFR), and it is also considered an indicator of not only renal damage but also \"systemic damage\" (generalized endothelial dysfunction, arterial remodeling, and increased cardiovascular risk) beyond the kidney. Furthermore, the reduction of proteinuria/albuminuria is clearly associated with a slower progression of CKD, making its reduction a therapeutic goal as well. Given this importance, this protocol aims to determine the urine albumin/creatinine ratio in all patients over 18 years old who visit their primary care physician in the province of Burgos, Spain, and require a blood test related to their reason for consultation.

Detailed description

This is a protocol in which we seek to identify those patients with alterations incipient renal failure by determining the albumin/creatinine ratio in urine, test that is currently performed routinely in different groups of patients. By For this reason, the implementation of the non-dialysis objective protocol hopes to be implemented standardized form in patients who go to their primary attention doctor in the province of Burgos to later be extended to the entire Castilla y Leon community. .

Conditions

• Chronic Kidney Disease (CKD)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	albumin creatinine ratio	Albumin creatinine ratio, this test is routinely performed in urine.

Timeline

• Start date: 2024-02-01
• Primary completion: 2024-10-01
• Completion: 2024-12-01
• First posted: 2024-06-06
• Last updated: 2024-06-06

Locations

1 site across 1 country: Spain