NCT06446765

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Mindfulness-based Neurofeedback to Augment Dialectical Behavior Therapy (DBT) for Adults With Borderline Personality Disorder (Aim 1)

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the ability of mindfulness-based real time functional magnetic resonance imaging (fMRI) neurofeedback (mbNF) to increase the benefits of evidence-based psychotherapy for adults with Borderline Personality Disorder (BPD).

Detailed description

The focus of this study is Aim 1.

Conditions

• Borderline Personality Disorder

Interventions

Type	Name	Description
BEHAVIORAL	mindfulness-based Neurofeedback	Participants will complete one session of mindfulness-based fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.
OTHER	control Neurofeedback	Participants will complete one session of control fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.

Timeline

• Start date: 2025-03-13
• Primary completion: 2026-05-30
• Completion: 2026-05-30
• First posted: 2024-06-06
• Last updated: 2025-06-05

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study