Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06445088

Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma

Evaluation of Diagnostic Performance of a Detection Kit for Epstein-Barr Virus C Promoter Methylation in Nasopharyngeal Carcinoma

Status
Recruiting
Phase
Study type
Observational
Enrollment
908 (estimated)
Sponsor
Sun Yat-sen University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This clinical study aims to evaluate the diagnostic performance of a new Epstein-Barr virus (EBV) C promoter methylation detection kit. All participants will undergo a series of diagnostic tests including VCA-IgA, EBNA1-IgA, and EBV-DNA assays. Additionally, nasopharyngeal swabs will be analyzed for EBV C promoter methylation. Confirmatory biopsy will be performed on all patients to establish a definitive diagnosis. This comprehensive approach seeks to assess the effectiveness of the methylation detection kit in a clinical setting.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTVCA-IgA, EBNA1-IgA, and EBV-DNADetect VCA-IgA, EBNA1-IgA, and EBV-DNA for all participants.
DIAGNOSTIC_TESTEBV C Promoter Methylation Detection in nasopharyngeal swab samplesDetection of methylation status of Epstein-Barr virus C promoter in human nasopharyngeal swab samples

Timeline

Start date
2024-05-29
Primary completion
2026-12-31
Completion
2026-12-31
First posted
2024-06-06
Last updated
2024-06-25

Locations

5 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06445088. Inclusion in this directory is not an endorsement.