NCT06442670

Understanding New Semantic Memory Learnings Across the Lifespan

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: University Hospital, Caen · Academic / Other
• Sex: All
• Age: 6 Years – 80 Years
• Healthy volunteers: —

Summary

The aim of this research is to specify the changes in brain connectivity (i.e. EEG phase synchronisation between brain regions) associated with semantic learning between individuals belonging to different age groups.

Detailed description

Semantic memory is a crucial concept in cognitive science. It has long been conceptualised as a static, amodal memory system containing knowledge about the world, concepts and symbols. Although recourse to this concept is inevitable, the mechanisms, both cognitive and neurobiological, that govern it are far from being elucidated. There are many debates and controversies in this fundamental field of cognitive science, and more specifically around the question of the acquisition and formation of knowledge in semantic memory. The literature on the development of semantic memory during ontogeny is full of contradictions. A review of this literature highlights the many unanswered questions surrounding semantic memory. How quickly is information encoded and then consolidated into a format that justifies the term semantic knowledge? What are the neural bases underlying the formation of knowledge in semantic memory? How does semantic knowledge evolve through new episodes? How do these mechanisms evolve during ontogeny? To what extent can some semantic learning be preserved from cognitive ageing? In the face of these many questions, the literature highlights the lack of tasks enabling semantic memory to be approached in an operational manner and the need to specify the cerebral mechanisms involved at different ages of life. The general hypotheses that will be tested as part of the ULIS project are as follows: 1. New semantic learning is possible independently of episodic memory processes. 2. This learning differs according to the age of the participants.

Conditions

• Neurodevelopmental Changes (Childhood, Ageing)

Interventions

Type	Name	Description
DEVICE	Electroencephalography	Phase synchrony during the completion of the semantic memory task

Timeline

• Start date: 2024-09-01
• Primary completion: 2026-05-01
• Completion: 2026-09-01
• First posted: 2024-06-04
• Last updated: 2024-06-04