NCT06442176

Choroid In Coronary Artery Disease

Choroid Thickness May Shed Light On Early Coronary Artery Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 128 (actual)
• Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital · Other Government
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Purpose: To investigate any relationship between choroid thickness (CTh) and coronary artery disease (CAD), particularly in its earlier stages before clinically evident. Design: Retrospective, cross-sectional observational study Methods: Setting: The study was performed in two institutions; patients were recruited in Balikesir City Hospital. The ophthalmological examinations and coronary angiograms were performed in Balikesir City Hospital. The analysis of the coronary angiograms including Gensini scoring were conducted in Bursa Education and Research Hospital. Study Population: The study group comprised 68 patients with documented CAD and 60 healthy control subjects. Patients with high myopia, cataracts, retinal vascular disease, retinal surgery, retinal dystrophy, laser photocoagulation, intravitreal anti-VEGF treatment, glaucoma, uveitis, retinal disorders, any systemic diseases were excluded from the study groups. Observation Procedure: Refractive examination, corrected visual acuity, intraocular pressure measurements, anterior and posterior segment examinations. Following measurements of macular thickness and retinal nerve fiber layer, choroidal thickness of both eyes was assessed by enhanced depth imaging optical coherence tomography.

Conditions

• Choroid Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	OCT	Enhanced depth imaging optical coherence tomography (EDI-OCT) using the Heidelberg Spectralis HRA + OCT (Heidelberg Engineering, Inc., Franklin, MA, USA)

Timeline

• Start date: 2021-03-01
• Primary completion: 2023-03-01
• Completion: 2024-04-21
• First posted: 2024-06-04
• Last updated: 2024-06-04

Locations

1 site across 1 country: Turkey (Türkiye)