NCT06441474

Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information in Women

Understanding and Addressing Rejection of Personalized Cancer Risk Information

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 750 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: Female
• Age: 39 Years – 74 Years
• Healthy volunteers: Not accepted

Summary

The Understanding and Addressing Rejection of Personalized Cancer Risk Information study is a longitudinal study conducted to understand the nature of phenomenon of personalized cancer risk rejection in the context of mammography screening.

Detailed description

The Understanding and Addressing Rejection of Personalized Cancer Risk Information study seeks to understand the nature of the phenomenon of personalized cancer risk rejection in the context of mammography screening by 1) identifying demographic and psychological factors associated with risk rejection and 2) identify how risk rejection influences risk-concordant mammography screening behavior. The study will test a priori theory-derived hypotheses about the precursors of risk rejection and the influence of rejection on real-life screening decision making. The Breast Cancer Risk Assessment Tool (BCRAT) will be used to asses participant's breast cancer risk. This model is designed to estimate breast cancer risk in women 35-84, and uses the following predictors: 1) age, 2) age at first menstrual period, 3) age at first live birth, 4) first-degree relatives with breast cancer, 5) previous breast biopsy with atypical hyperplasia, and 6) race/ethnicity. Participants will be required to complete the baseline survey in which they receive their BCRAT model risk estimate and respond to that risk estimate. They will then complete a 12-month follow-up survey.

Conditions

• Breast Cancer Female

Interventions

Type	Name	Description
BEHAVIORAL	Presentation of personal breast cancer risk estimate	All participants will be presented with their personal breast cancer risk estimate, calculated using the Gail Model

Timeline

• Start date: 2025-04-02
• Primary completion: 2027-04-02
• Completion: 2028-04-02
• First posted: 2024-06-04
• Last updated: 2026-02-27

Locations

2 sites across 1 country: United States