Trials / Completed
CompletedNCT06441409
Effect of Lifestyle Intervention on Mobilization of Fat Storage and Iron Deposition in Obesity
Effect of Calorie-restricted Balanced Diet on Mobilization of Fat Storage Pools and Iron Deposition in Individuals With Obesity
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 160 (actual)
- Sponsor
- The Third Xiangya Hospital of Central South University · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
The goal of this clinical trial is to learn if calorie-restricted balanced diet could uniquely influence various fat storage pools and iron deposition and explore the relationships between fat or iron deposition loss in specific locations and glucose metabolism. The main questions it aims to answer are: After lifestyle intervention, which part of the body shows the fastest fat mobilization? Which part shows the slowest fat mobilization? Which area's fat mobilization is most related to the alleviation of glucose metabolism? Is there a relationship between the fat deposition in organs and the iron deposition in organs? Researchers will compare the liver fat, pancreatic fat, visceral fat, subscutaneous fat, liver and pancrease iron depositon after lifestyle intervention using self pre-and post-control . Participants will: Receive the lifestyle intervention in outpatient. Visit the clinic once after 6 months for checkups and tests. Keep a diary of their diet.
Detailed description
Fat mobilization status is assessed using magnetic resonance, while the relief of glucose metabolism is determined based on the results of the OGTT before and after life style intervention.
Conditions
- Liver Fat
- Fertility Disorders
- Life Style, Healthy
- Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Lifestyle intervention | Patients were intervened with lifestyle only and returned to clinic for tests in 6 months. Lifestyle intervention included the diet and exercise. Diet was an energy-restricted balanced diet. Exercise requires 5 days a week and 30 minutes every day. |
Timeline
- Start date
- 2024-04-15
- Primary completion
- 2025-04-20
- Completion
- 2025-04-28
- First posted
- 2024-06-04
- Last updated
- 2025-08-07
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06441409. Inclusion in this directory is not an endorsement.