NCT06440772

Portal Vein Pulsatility Index to Assess Fluid Intolerance

Assessing Fluid Intolerance Using Portal Vein Pulsatility Index Post-Passive Leg Raising Test in Fluid Responders: A Prospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study uses the portal vein pulsatility index (PVPI) to assess fluid intolerance amongst fluid responders.

Detailed description

This prospective observational study aims to use the portal vein pulsatility index (PVPI) to assess fluid intolerance in fluid responders. The investigators will enroll mechanically ventilated postoperative adult patients within 6 hours of ICU admission after cardiac surgery. Patients will undergo a Passive Leg Raising (PLR) test and Left Ventricular Outflow Tract (LVOT) recording using transthoracic echocardiography. The main objective is to predict fluid intolerance after a fluid challenge of 7 ml/kg Ringer Lactate over 10 minutes in initially tolerant fluid responders.

Conditions

• Venous Congestion

Interventions

Type	Name	Description
DRUG	Ringer's Lactate Crystalloid Solutions	7 ml/kg ml of Ringer's Lactate is given in 10 min amongst initially tolerant fluid responders.

Timeline

• Start date: 2023-05-01
• Primary completion: 2024-07-01
• Completion: 2024-07-01
• First posted: 2024-06-04
• Last updated: 2024-08-27

Locations

1 site across 1 country: Romania