NCT06436417

Functional Capacity Through HRV in Multimodal Rehabilitation for Adult Surgery

Monitoring Functional Capacity Through Heart Rate Variability Within the Multimodal Rehabilitation Program in Adult Surgery

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 490 (estimated)
• Sponsor: Investigation Group Anesthesia, Resuscitation, And Perioperative Medicine of Aragon · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This prospective, observational cohort study investigates heart rate variability (HRV) monitoring using the Analgesia Nociception Index (ANI) monitor in adult patients undergoing major surgery within a multimodal rehabilitation program. The objective is to correlate HRV indices with functional capacity, physiological reserve, and frailty during the prehabilitation phase.

Detailed description

The study evaluates HRV using the ANI monitor to determine adaptation to training load, optimize analgesic and anesthetic dosing, and predict postoperative complications. The HRV indices of Energy (SDNN) and ANI (HFnu) are monitored at two points: the initial pre-anesthesia consultation and one week before surgery. Results will be compared with the 6-minute walk test, MUST nutrition screening scale, and clinical frailty and FRAIL scales.

Conditions

• Frailty in Adult Surgery

Interventions

Type	Name	Description
DEVICE	Analgesia Nociception Index (ANI) Monitor	Non-invasive monitoring of HRV to evaluate autonomic nervous system activity using the indices of Energy (SDNN) and ANI (HFnu).
BEHAVIORAL	Trimodal Prehabilitation	Program of physical exercise, nutritional supplementation, and psychological support according to the RICA guidelines of the Spanish Group for Multimodal Rehabilitation.

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-06-01
• Completion: 2025-12-01
• First posted: 2024-05-31
• Last updated: 2024-05-31

Locations

1 site across 1 country: Spain