NCT06436170

The Role of Radial Peripapillary Vessel Density in Irvine-gass Syndrome

Radial Peripapillary Vessel Density as a New Biomarker in Irvine-Gass Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 58 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Pseudophakic cystoid macular edema (PCME), also known as Irvine-Gass syndrome (IGS), is an accumulation of fluid in the macula that occurs after cataract surgery, with an early or late presentation (cut-off 3 months) . It is the most common cause of decreased vision after uneventful phacoemulsification, with a rare incidence of 0.1-2.35% for clinically significant PCME . Macular edema in IGS can be diagnosed and classified by optical coherence tomography (OCT), which enables its morphologic assessment. Fluorescein angiography (FA) is the gold standard to perform differential diagnosis for macular edema. To date, OCT angiography (OCTA) has been proposed to study various retinal vascular diseases. In contrast to FA, OCTA is able to visualize Radial peripapillary vessel density (RCP). The aim of this study was to investigate abnormalities in the vascular network of the optic nerve head in patients with IGS compared to healthy eyes, using OCT-A

Conditions

• Cataract
• Macular Edema

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	OCTA	OCTA is a non invasive diagnostic technique to visualize RPC

Timeline

• Start date: 2023-07-01
• Primary completion: 2023-12-30
• Completion: 2024-04-29
• First posted: 2024-05-30
• Last updated: 2024-05-30

Locations

1 site across 1 country: Italy