NCT06433375

Evaluation of the Efficacy of Growth Hormone, EndoSeal MTA Sealer, and Their Combination on Healing of Periapical Pathosis

Evaluation of the Efficacy of Growth Hormone, EndoSeal MTA Sealer, and Their Combination on Healing of Periapical Pathosis(Non-Surgical Approach)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: Male
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study aimed to evaluate the effect of growth hormone, EndoSeal MTA sealer, and their combination on Healing of Periapical Pathosis.

Detailed description

Out of 100 healthy male patients aged 18 to 40 years, 32 were selected from outpatients attending the Endodontic Clinic of the Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt, to be included in this study. The selected patients have no medical contraindications for oral surgical procedures (Scores 1-2) according to the classification of the American Society of Anesthesiologists (ASA)(8). Single-rooted permanent teeth were selected according to specific inclusion criteria based on preoperative assessment of the patients.

Conditions

• Growth Hormone
• EndoSeal MTA
• Periapical Pathosis

Interventions

Type	Name	Description
PROCEDURE	Growth hormone application	Growth hormone application during non-surgical root canal treatment
PROCEDURE	Root canal treatment	Teeth undergo conventional root canal treatment without any additional intervention

Timeline

• Start date: 2023-04-01
• Primary completion: 2024-04-01
• Completion: 2025-04-01
• First posted: 2024-05-29
• Last updated: 2025-07-29

Locations

1 site across 1 country: Egypt