NCT06433115

Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: University of Missouri-Columbia · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study is investigating the benefits of lean beef consumption on cardiometabolic health and gut microbiome.

Detailed description

The study is a 6-wk randomized, controlled, and parallel arm clinical trial. Participants will be randomized to consume either lean grain-fed beef, lean grass-fed beef, or plant-based meat for 6 weeks. Outcomes assessed will include metabolic, inflammatory, and gut microbiome markers.

Conditions

• Diet Intervention

Interventions

Type	Name	Description
OTHER	Lean (≥90%) Grass-Fed Beef	The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
OTHER	Lean (≥90%) Grain-Fed Beef	The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
OTHER	Plant-Based Meat	Plant-based meat would be macronutrient matched to the same quantities of meat prescribed for a given energy level.

Timeline

• Start date: 2024-06-11
• Primary completion: 2027-12-01
• Completion: 2027-12-01
• First posted: 2024-05-29
• Last updated: 2025-08-01

Locations

1 site across 1 country: United States