NCT06432387

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair (CoFA-TAAA); a Prospective Observational Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 58 (estimated)
• Sponsor: University of Thessaly · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will evaluate the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.

Detailed description

Endovascular aneurysm repair of abdominal aorta activates a significant inflammation reaction and has an impact on coagulation. Platelet activation seems to have a major role in this prothrombotic and hypercoagulable state. In complex thoraco-abdominal aortic aneurysm repair the implants are more complexed and the duration of operation longer. The main hypothesis is that all the above have a greater impact on platelet activation and coagulation alterations. The aim of this study is the evaluation of the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.

Conditions

• Thoraco-abdominal Aortic Aneurysm Repair
• Coagulation Factors Alterations
• Platelet Activation

Interventions

Type	Name	Description
OTHER	Patients undergoing complex thoraco-abdominal aortic aneurysm repair	Patients undergoing complex thoraco-abdominal aortic aneurysm repair

Timeline

• Start date: 2024-05-31
• Primary completion: 2025-12-31
• Completion: 2026-01-15
• First posted: 2024-05-29
• Last updated: 2024-06-03

Locations

1 site across 1 country: Greece