NCT06431282

Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment

In Vivo Visualisation of Hyaluronic Acid After CO2 Laser Compared to Thulium Laser Treatment

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

* Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days. * Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.

Conditions

• Aging Skin

Interventions

Type	Name	Description
OTHER	CO2 laser + HA	Probands will be treated with a CO2 laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
OTHER	Thulium laser + HA	Probands will be treated with a thulium laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.

Timeline

• Start date: 2024-02-20
• Primary completion: 2024-05-31
• Completion: 2024-06-30
• First posted: 2024-05-28
• Last updated: 2024-05-28

Locations

1 site across 1 country: Germany