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Trials / Active Not Recruiting

Active Not RecruitingNCT06425991

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

A Phase 1 Randomized, Open Label Pharmacokinetic Comparability Study Comparing Pre- and Post-change Teclistamab in Participants With Relapsed/Refractory Multiple Myeloma

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
108 (actual)
Sponsor
Janssen Research & Development, LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the pharmacokinetics (processes by which drugs are absorbed, distributed in the body, and excreted) between teclistamab made from the current commercial manufacturing process (pre-change) and the new manufacturing process (post-change).

Conditions

Interventions

TypeNameDescription
DRUGTeclistamabTeclistamab will be administered subcutaneously.

Timeline

Start date
2024-06-07
Primary completion
2027-02-28
Completion
2027-03-03
First posted
2024-05-23
Last updated
2026-04-13

Locations

53 sites across 11 countries: United States, Australia, Canada, France, Germany, Israel, Italy, Poland, South Korea, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06425991. Inclusion in this directory is not an endorsement.