NCT06422182

Erector Spinae Plane Block in Radical Cystectomy

Ultrasound-Guided Erector Spinae Plane Block in Radical Cystectomy: A Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this research is to study and compare the efficacy and safety of bilateral single injection erector spinae plane block (ESPB) compared with intravenous patient-controlled analgesia (IV-PCA) in managing postoperative pain after radical cystectomy.

Detailed description

Radical cystectomy (RC) is one of the most challenging surgical techniques in Urology. Acute postsurgical pain is frequently detrimental in a patient's recovery and quality of life. Intravenous patient-controlled analgesia (IV-PCA) is one of the most commonly used strategies in clinical practice for controlling postoperative pain. It involves continuous administration of a programmed dose of analgesics, while also allowing patients to receive additional, need-based doses. One such avenue is the erector spinae plane block (ESPB), a novel analgesic technique first described in 2016 by Forero et al. Although the mechanism of action of the ESPB is unknown, a proposed mechanism is via blockade of the dorsal and ventral rami of thoracic/lumbar spinal nerves. ESPB has been used as analgesia in rib fractures and other thoracic procedures as well as in abdominal surgeries.

Conditions

• Erector Spinae Plane Block
• Radical Cystectomy

Interventions

Type	Name	Description
DRUG	Bupivacain 25% (Erector Spinae Plane Block)	Patients received ultrasound guided bilateral single shot erector spinae pane block (ESPB) at Th10 level with 20 mL 0.25% bupivacaine after the end of surgery.
DRUG	Morphine (Intravenous patient-controlled analgesia)	Patients received intravenous patient-controlled analgesia (IV-PCA) by morphine

Timeline

• Start date: 2021-07-25
• Primary completion: 2024-01-15
• Completion: 2024-01-15
• First posted: 2024-05-20
• Last updated: 2024-05-21

Locations

1 site across 1 country: Egypt