NCT06421415

Long Term Effect of AIT in Children

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Odense University Hospital · Academic / Other
• Sex: All
• Age: 4 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or venom.

Detailed description

The study will include children aged 5- 18 years who are treated with immunotherapy at Hans Christian Andersen Children' Hospital, Odense University Hospital. Informed consent to be registered in a database and to receive a questionnaire 5 and 10 years after end of treatment are obtained before start of immunotherapy. Base line data include information from the patient record: symptoms, medication, blood test and skin prick test results. During treatment effect, medication use, lung function and adverse events are monitored systematically once a year. The questionnaires 5 and 10 years after end of treatment will focus on allergy symptoms, use of medication and asthma symptoms.

Conditions

• Allergy in Children

Interventions

Type	Name	Description
DRUG	Allergen Immunotherapy Extract	Patients will be treated as usual. The study is an observation of the long term effect of the treatment

Timeline

• Start date: 2024-05-01
• Primary completion: 2036-12-01
• Completion: 2037-05-01
• First posted: 2024-05-20
• Last updated: 2025-07-10

Locations

2 sites across 1 country: Denmark