NCT06420284

Immunological Parameters Between MRONJ Stages

Characterization of Immunological Parameters in Different Clinical Stages of Medication-Related Osteonecrosis of the Jaw

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 42 (estimated)
• Sponsor: Marmara University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study aims to conduct a detailed analysis of the immunological response profiles that emerge at different clinical stages of medication-related osteonecrosis of the jaw (MRONJ). The research seeks to understand how these responses influence the pathogenesis, staging, and treatment of MRONJ. Throughout the study, cytokine levels, inflammation markers, and other immunological parameters observed at various stages will be comprehensively assessed. The results of these analyses are expected to provide insights into how stage-specific immunological variables could play a role in the diagnosis and treatment of MRONJ.

Conditions

• Medication-Related Osteonecrosis of Jaw

Timeline

• Start date: 2024-05-01
• Primary completion: 2025-02-01
• Completion: 2025-05-01
• First posted: 2024-05-20
• Last updated: 2024-05-20

Locations

1 site across 1 country: Turkey (Türkiye)