NCT06419998

Transanal Versus Laparoscopic-assisted Transanal Through in the Management of Hirschsprung's Disease

One Stage Transanal Versus One Stage Laparoscopic-assisted Transanal Endorectal Pull-through in the Management of Hirschsprung's Disease in Pediatric Age Group; A Retrospective Study.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Egyptian Biomedical Research Network · Network
• Sex: All
• Age: 3 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare the surgical and functional outcomes of pure transanal endorectal pull-through (TAERPT) and laparoscopic-assistance endorectal pull-through (LAERPT) in pediatric patients presented with Hirschsprung's Disease between 3 months and 18 years old. The main questions our study aims to answer are: * Does post-operative continence differs between the two groups? * Does post-operative constipation differs between the two groups? * Does post-operative soiling differs between the two groups * Does post-operative enterocolitis differs between the two groups? * Do post-operative complications differ between the two groups? If there is a comparison group: Researchers will compare between pure transanal endorectal pull-through (TAERPT) and laparoscopic-assistance endorectal pull-through (LAERPT) to see if there is a difference in post-operative continence, constipation, soiling, enterocolitis or complications. Participants will be divided into two groups; 40 patients will be treated by TAERPT and included in Group A and 30 patients will be treated by LAERPT and included in Group B.

Detailed description

Introduction: One-stage treatment of endorectal pull-through for Hirschsprung's disease could be approached through a complete transanal approach or with the assistance of laparoscopy. Our study aims to compare the surgical and functional outcomes of pure transanal endorectal pull-through (TAERPT) and laparoscopic-assistance endorectal pull-through (LAERPT). Material \& methods: This retrospective study included 70 pediatric patients presented with Hirschsprung's Disease to Elshatby University Hospital. 40 patients were treated by TAERPT and included in Group A and 30 patients were treated by LAERPT and included in Group B. The two groups were compared as regards the operative data as well as the post-operative outcomes including the time of passage of stools, time of tolerating oral feeding, the duration of hospital stay, and the development of any early postoperative complications. Also, the number of bowel habits, constipation, enterocolitis, abdominal distension, anastomotic stricture, and continence were assessed.

Conditions

• Pediatric Disorder
• Hirschprung's Disease

Interventions

Type	Name	Description
PROCEDURE	Group A: Pure transanal endorectal pull-through (TAERPT)	Patients of Group A will be treated totally by pure transanal endorectal pull-through without the assistance of laparoscopy
PROCEDURE	Group B: Laparoscopic-assistance endorectal pull-through (LAERPT)	Patients of Group B will be treated transanal endorectal pull-through but with the assistance of laparoscopy

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-12-01
• Completion: 2023-12-01
• First posted: 2024-05-17
• Last updated: 2024-05-21

Locations

1 site across 1 country: Egypt