NCT06419478

Postoperative Symptoms in Chinese Liver Cancer Patients: Network Analysis

Exploring Early Postoperative Core Symptoms in Chinese Patients With Primary Liver Cancer: a Cross-sectional and Longitudinal Network Analysis

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 249 (actual)
• Sponsor: Mengmeng Yuan · Academic / Other
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Patients with primary liver cancer (PLC) experience a range of symptoms in the early postoperative period. Symptoms include cancer-related symptoms and adverse effects of treatment. Exploring the core symptoms and their dynamics in the early post-hepatectomy patients may help provide better symptom management programs. The purpose of this study was to identify the core symptoms in early post-hepatectomy patients and to explore the trajectory of their dynamics. During the period from March 2021 to September 2022, a total of 281 patients diagnosed with PLC and undergoing radical curative surgery were recruited from the hepatobiliary surgery departments of two hospitals in Eastern China, among whom 249 individuals (88.60%) agreed to participate in the study. A comprehensive symptom assessment was administered to the patients 1-2 days after surgery (T1) and 1-2 days before discharge (T2). Network analysis was used to identify core symptoms in early post-hepatectomy patients based on symptom severity.

Conditions

• Patients With Primary Liver Cancer (PLC) Undergoing Curative Surgical Procedures
• Importance of Identifying Core Symptoms for Improving Symptom Management in PLC Patients
• Application of Network Analysis as a Crucial Component of Cancer Care

Interventions

Type	Name	Description
OTHER	postoperative symptoms	Observational study, focusing solely on symptom surveys of patients.

Timeline

• Start date: 2021-03-01
• Primary completion: 2022-08-31
• Completion: 2022-09-01
• First posted: 2024-05-17
• Last updated: 2024-05-17

Locations

1 site across 1 country: China