Trials / Completed
CompletedNCT06419283
Prospective Study on Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction
Evaluation of the Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction: a Prospective Study
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 59 (actual)
- Sponsor
- Huizhou Municipal Central Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this clinical study is to evaluate the safety and efficacy of stenting for revascularization treatment of chronic middle cerebral artery (MCA) occlusion in patients with chronic MCA occlusion. The main questions it aims to answer are: 1. Whether stenting treatment can improve blood flow restoration in chronic MCA occlusion. 2. If stenting can reduce the rates of reocclusion. 3. How stenting affects the recovery of neurological functions in these patients. Researchers will compare the stenting group, which received stenting revascularization in addition to aspirin treatment, to the control group, which received only aspirin treatment to see if stenting treatment provides superior outcomes in terms of neurological function improvement and safety profile. Participants will: 1. Undergo full cerebral angiography to identify the occlusion site. 2. All participants will be monitored for post-procedure complications and neurological function using the Modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) before and after treatment. 3. Participants will be followed up for three months post-treatment to assess the long-term efficacy and safety of the stenting procedure.
Conditions
- Chronic Middle Cerebral Artery Occlusion
- Stenting Treatment
- Modified Rankin Scale
- National Institutes of Health Stroke Scale
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Middle Cerebral Artery Stent Implantation | Middle Cerebral Artery Stent Implantation |
| DRUG | standard treatment with aspirin. | standard treatment with aspirin. |
Timeline
- Start date
- 2019-08-01
- Primary completion
- 2022-12-01
- Completion
- 2024-03-01
- First posted
- 2024-05-17
- Last updated
- 2024-05-17
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06419283. Inclusion in this directory is not an endorsement.