NCT06416488

High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children

The Effect of High-Intensity Interval Training(HIIT) on Cardio-metabolic Indicators in School-age Children With High Cardiovascular Diseases Risk--a Randomised Intervention Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 336 (estimated)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: All
• Age: 7 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and acceptability of HIIT in this population for future application.

Detailed description

Evidence shows that physical activity is positively associated with cardiovascular and metabolic health in children and adolescents, including promoting lipid health, regulating blood pressure levels, and glucose metabolism. Physical activity intervention for overweight or obese children can lower body mass index, total fat mass, and abdominal fat mass, and further prevent chronic diseases such as cardiovascular and metabolic diseases. High-intensity interval training (HIIT) has been a recent research focus. Previous studies have demonstrated that HIIT can contribute to improving body composition, reducing visceral fat, and enhancing cardiovascular and pulmonary function. Moreover, compared to other trainings, HIIT is time-efficient and adaptable to various sports, thus leading to higher compliance. However, there has been a lack of evidence regarding the intervention effects of this exercise in overweight and obese children and adolescents, and whether it can impact or even reverse cardio-metabolic risks remains unknown. Therefore, this intervention trial might have implications and practical significance on the feasibility of promoting HIIT among this population.

Conditions

• Cardiovascular Syndrome, Metabolic

Interventions

Type	Name	Description
BEHAVIORAL	HIIT intervention	Modified HIIT in Tabata mode, which followed a pattern of 3 sets, with each set consisting of 4 repetitions of 20 seconds of high-intensity exercise followed by 10 seconds of rest, at least 3 times per week.
BEHAVIORAL	General health education	General instructions on promoting healthy diet and exercise, primarily by sending offline and online promotion materials to participants.

Timeline

• Start date: 2024-07-13
• Primary completion: 2027-09-01
• Completion: 2028-09-01
• First posted: 2024-05-16
• Last updated: 2025-12-16

Locations

1 site across 1 country: China