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Enrolling By InvitationNCT06415344

Long-term Extension of GTX-102 in Angelman Syndrome

A Long-term Extension Trial Investigating the Safety and Efficacy of GTX-102 in Patients With Angelman Syndrome

Status
Enrolling By Invitation
Phase
Phase 3
Study type
Interventional
Enrollment
255 (estimated)
Sponsor
Ultragenyx Pharmaceutical Inc · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to evaluate the long-term safety profile of GTX-102 in participants with Angelman Syndrome (AS)

Detailed description

This study is a phase 3, long term extension (LTE) which is open to participants rolling over from a prior GTX-102 clinical study. The LTE study will evaluate the long-term safety and efficacy of GTX-102 in participants with AS.

Conditions

Interventions

TypeNameDescription
DRUGGTX-102Antisense Oligonucleotide

Timeline

Start date
2024-07-31
Primary completion
2029-02-01
Completion
2029-02-01
First posted
2024-05-16
Last updated
2026-01-07

Locations

23 sites across 8 countries: United States, Australia, Canada, France, Germany, Israel, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06415344. Inclusion in this directory is not an endorsement.

Long-term Extension of GTX-102 in Angelman Syndrome (NCT06415344) · Clinical Trials Directory