NCT06413641

VIsualization of Coronary Artery Disease for Modification of RISK Factors

VIsualization of Coronary Artery Disease for Modification of RISK Factors. Prevention of Disease Progression in Patients With Non-Obstructive Coronary Atherosclerosis.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 273 (estimated)
• Sponsor: Aarhus University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The VICAD-RISK study assesses if visualization of coronary CT angiography (CTA) images in participants with non-obstructive coronary artery disease will improve LDL lowering, reduce reporting of side effects by cholesterol lowering medications, and modify the coronary artery disease phenotype over 12 months.

Detailed description

In Denmark non-obstructive coronary artery disease is found in 35-40% of patients undergoing coronary CT angiography for suspected coronary artery disease. Modification of risk factors is essential in patients with coronary artery disease to prevent major cardiovascular events. However, in non-obstructive coronary artery disease, initiation and adherence to treatment with lipid lowering therapy is poor. The study will include 273 patients from 5 different sites; patients will be randomized into 3 groups; standard follow up by general practice, structured disease education or the combination of the latter with visualization of coronary CT angiography images. A follow-up CT angiography will be performed at 12 months.

Conditions

• Coronary Artery Disease
• Non-Obstructive Coronary Atherosclerosis

Interventions

Type	Name	Description
OTHER	Follow up at general practice	As described before
OTHER	Consultation	As described before
OTHER	Visualization of CTA images	As described before

Timeline

• Start date: 2024-03-12
• Primary completion: 2025-08-31
• Completion: 2026-08-31
• First posted: 2024-05-14
• Last updated: 2025-02-19

Locations

5 sites across 1 country: Denmark