NCT06406998

Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD

Maternal and Offspring Outcomes in Pregnant Women With Pre-existing Atherosclerotic Cardiovascular Disease: A Nationwide Mother-Child Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5,461,222 (estimated)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: —

Summary

A growing body of evidence supports associations between cardiovascular health and adverse pregnancy outcome and between adverse pregnancy outcome and atherosclerotic cardiovascular disease and builds on the well-established pathways known to exist between cardiovascular health and atherosclerotic cardiovascular disease across the life course and intergenerationally. Furthermore, previous studies frequently lack comprehensive long-term follow-up, making it difficult to assess the enduring impacts of maternal cardiovascular health on postpartum outcomes and long-term maternal and child health.

Detailed description

the current study aimed to evaluate the associations between maternal pre-existent atherosclerotic cardiovascular disease and adverse pregnancy outcomes, and the combined effect of maternal pre-existent atherosclerotic cardiovascular disease and adverse pregnancy outcomes on the risk of long-term adverse events of offspring.

Conditions

• Cardiovascular Diseases
• Atherosclerosis
• Pregnancy Complications
• Adverse Cardiac Event
• Adverse Birth Outcomes

Interventions

Type	Name	Description
OTHER	Pre-existing atherosclerotic cardiovascular disease	Presence of pre-existing atherosclerotic cardiovascular disease

Timeline

• Start date: 2021-01-01
• Primary completion: 2024-07-31
• Completion: 2024-12-31
• First posted: 2024-05-09
• Last updated: 2024-05-09

Locations

1 site across 1 country: South Korea