Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06400290

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
Imperial College London · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

ORBITA-MOON is a double-blinded, placebo-controlled experimental study that aims to understand how the different coronary artery stenoses contribute to overall clinical angina in patients with multi-vessel coronary artery disease. This study will investigate the symptoms conferred by each stenosis, induced by experimental ischaemia, for 60 patients with multi-vessel coronary artery disease.

Conditions

Interventions

TypeNameDescription
PROCEDUREPercutaneous coronary intervention (PCI)Coronary artery stenting for stable angina
DIAGNOSTIC_TESTSymptom assessment during experimentally induced ischaemiaTransient experimental balloon occlusion across coronary stenosis to determine the symptoms conferred by ischaemia at this stenosis.

Timeline

Start date
2024-06-13
Primary completion
2027-01-01
Completion
2027-04-01
First posted
2024-05-06
Last updated
2025-06-06

Locations

9 sites across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT06400290. Inclusion in this directory is not an endorsement.