NCT06400030

A Comparison Between Two Types of Sealers in the Healing of Periapical Lesions

The Effects of BioCeramic Sealer With Single Cone Technique on the Healing of Periapical Lesions: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Damascus University · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions. The study sample will consist of 41 patients with 65 teeth with clear periapical lesions. Root canal obturation will be applied for all patients. BioCeramic sealer will be applied for the experimental group only. The changes of the dimensions of the periapical lesion will be assessed using CBCT radiographs; pre- and post- treatment changes for each group will be evaluated individually.

Detailed description

Periapical lesions is considered as the most common symptoms associated with infected root canals. Recently, the BioCeramic sealer has been considered one of the most common endodontic sealer that possess antibacterial properties, so it can have an effective role in the healing of periapical lesions, as well as its ability to prevent periapical leakage due to its attachment to the dentinal walls and gutta-percha cones. This study will evaluate the effect of BioCeramic sealer on the healing of periapical lesions and the changes of the dimensions of the lesions. Root canal obturation with gutta-percha cones will be applied in the two groups: The control group will receive the AH Plus with lateral condensation technique, and the experimental group will receive BioCeramic sealer with single cone technique. CBCT radiographs will be gotten before and after one year of the treatment to evaluate the periapical lesion dimensions changes.

Conditions

• Periapical Lesions

Interventions

Type	Name	Description
PROCEDURE	Root canal treatment with AH Plus sealer	\- AH Plus sealer Group: the base and accelerator of AH Plus Sealer was mixed, then the walls of the canal were coated with the AH Plus sealer using K-File, then lateral condensation was performed through a number of gutta-percha cones.
PROCEDURE	Root canal treatment with BioCeramic sealer	\- BioCeramic Sealer Group: the canals in this group were filled using BioCeramic-based sealer and a single gutta-percha cone, and gently insert it into the root canal to the preselected working length without applying pressure.

Timeline

• Start date: 2020-06-22
• Primary completion: 2022-03-01
• Completion: 2023-04-15
• First posted: 2024-05-06
• Last updated: 2024-05-06

Locations

1 site across 1 country: Syria