Trials / Recruiting
RecruitingNCT06398938
Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy
EROS 3 Study Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy Brachytherapy in Terms of Overall Toxicity and Sexual Activity
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 129 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
To evaluate the degree of acute and long-term intestinal, urinary and vaginal toxicity, and the impact on sexual activity of an accelerated fractionation of high dose rate interventional radiotherapy (IRT-HDR) in patients with locally advanced cervical cancer (IB2 - VA, N+/-).
Detailed description
Observational, monocentric and prospective study. All patients with locally advanced cervix cancer will be underwent to radiochemotherapy followed by accelerated interventional radiotherapy (brachytherapy). Fist endpoints wer severe acute and late gastrointestinal, and urinary toxicities and sexual activity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Interventional Radiotherapy | The patients will undergo four IRT fractions in one week |
Timeline
- Start date
- 2024-05-06
- Primary completion
- 2025-05-30
- Completion
- 2026-12-30
- First posted
- 2024-05-03
- Last updated
- 2025-08-15
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06398938. Inclusion in this directory is not an endorsement.