NCT06395259

Observational Study on the Variation of Ascorbic Acid in Patients Undergoing Solid Organ Transplantation

Evaluation of the Oxidative Status of Patients Undergoing Solid Organs Transplantation: Observational Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Policlinico Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this observational clinical study is to evaluate the variations in ascorbic acid during the transplantation phases and how these variations influence the oxidative status and patient outcome. The main questions it aims to answer are: * how many patients arrive at the transplant in a state of hypovitaminosis C? * how does hypovitaminosis C affect the patient's oxidative status? * how does hypovitaminosis C affect the length of stay in intensive care and post-transplant complications?

Detailed description

Researches will compared: Differences between Hypovitaminosis Group and Normal Range Group Changes in oxidative stress markers before and after solid organ transplantation Incidence of allograft dysfunction between groups Incidence of acute kidney injury and other complications between groups

Conditions

• Transplantation
• Ascorbic Acid Deficiency

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-08-31
• Completion: 2024-08-31
• First posted: 2024-05-02
• Last updated: 2024-09-04

Locations

1 site across 1 country: Italy