Trials / Completed
CompletedNCT06394466
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
Evaluation of Thyroid Function and Autoimmunity in Subfertility Women and Thyroid Hormone Levels in the First Trimester of Assisted Reproduction
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 453 (actual)
- Sponsor
- Rio de Janeiro State University · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of low-grade inflammation. There are no studies about the detection of these autoantibodies in infertile women. Our objective is to evaluate the association between ovarian reserve and thyroid function and its autoimmunity in infertile women seeking for assisted reproductive treatment (ART).Evaluation ot thyroid function in the first trimester in also be evaluated in women submitted to ART.
Detailed description
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of low-grade inflammation. There are no studies about the detection of these autoantibodies in infertile women. Evaluation of TSH profile during ovarian stimulation in ART is also debated in literature with conflicting results. Our objective is to evaluate the association between ovarian reserve and thyroid function and its autoimmunity in infertile women seeking for assisted reproductive treatment (ART) and TSH profile during ovarian stimulation and during the first trimester.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Non Applicable | Non Applicable |
Timeline
- Start date
- 2021-07-01
- Primary completion
- 2023-07-31
- Completion
- 2023-07-31
- First posted
- 2024-05-01
- Last updated
- 2024-05-01
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT06394466. Inclusion in this directory is not an endorsement.