NCT06394375

Opioid Free Anesthesia in Abdominal Laparoscopic Surgery

Effectiveness of Opioid Free Anesthesia Using Dexmedetomidine Inhibiting Nociception in Abdominal Laparoscopic Surgery

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Effectiveness of opioid free anesthesia using Dexmedetomidine to inhibit nociception in abdominal laparoscopic surgery

Detailed description

Abdominal laparoscopic surgery is one of the most common procedures worldwide, commonly facilitated with opioid balanced anesthesia or regional anesthesia. Despite being a controversy, there are issues that suggest opioid to have an influence in tumor recurrence. The investigators performed general anesthesia without opioid in laparoscopic abdominal surgery, and compared the hemodynamic instability, total consumption of fentanyl rescue, qNOX score, Ephedrine intraoperative, and Numerical Rating Scale.

Conditions

• Laparoscopic Surgery
• Abdominal Surgery

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	OFA
DRUG	Fentanyl	Given as analgesia in opioid balanced anesthesia (control) group

Timeline

• Start date: 2023-07-01
• Primary completion: 2023-10-31
• Completion: 2023-12-31
• First posted: 2024-05-01
• Last updated: 2024-05-03

Locations

1 site across 1 country: Indonesia