NCT06393634

Comparing Direct and Indirect Detection Methods of Multiple Routes of Testosterone Administration

Comparing Direct and Indirect Detection Methods Following Multiple Routes of Testosterone administration-an Anti-doping Perspective

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Sports Medicine Research and Testing Laboratory · Industry
• Sex: Male
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Testosterone abuse is extremely prevalent in athletes globally and especially in the United States professional sporting leagues

Detailed description

Because human bodies make testosterone naturally, it can be difficult to determine whether the testosterone in your body is natural or if it came from administering testosterone. Currently, testosterone abuse by athletes is detected by anti-doping laboratories in urine samples and use can also be inferred by testing blood samples. As a pharmaceutical preparation, testosterone is available to administer to your body in different ways. However, due to lack of controlled data on the various preparations of testosterone administrations related to the anti-doping field, this study id designed to look at five different testosterone preparations delivered three different ways and how they compare to each other in terms of anti-doping detection and how long they will be in circulation in your body.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Testosterone injection	A single injection of testosterone
DRUG	Testosterone gel	A daily dose of testosterone gel
DRUG	Testosterone Oral	A twice-daily pill of testosterone pill to swallow

Timeline

• Start date: 2024-11-27
• Primary completion: 2024-11-27
• Completion: 2024-11-27
• First posted: 2024-05-01
• Last updated: 2024-12-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study