NCT06392399

Interventions for the Management of Perineal Cancer Pain

Cooled Radiofrequency in Comparison to Either Conventional Radiofrequency Thermocoagulation or Neurolytic Block of Ganglion Impar in the Management of Perineal Cancer Pain

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Pain associated with neoplasms may be of somatic, visceral, or neuropathic origin.Visceral pain or pain that is mediated by the sympathetic fibers in the perineal area associated with malignancy in the pelvis may be effectively treated with neurolysis of impar ganglion.In recent years, radiofrequency lesioning of the ganglion Impar has evolved as a novel non pharmacological technique for the management of patients suffering from intractable perineal pain.

Conditions

• Cancer Rectum
• Cancer Vulva
• Cancer Vagina

Interventions

Type	Name	Description
DEVICE	cooled radiofrequency ,	In Cooled RF, after placement of the introducer needle, the 18 gauge internally cooled RF electrode is used for 90 seconds at a temperature of 60°C.
DEVICE	conventional radiofrequency	In conventional RF group lesion will be performed at 80°C for 120 seconds.
DEVICE	neurolysis of ganglion	In neurolytic block, Once the position of the needle tip confirmed, 4 - 6 mL of 8% phenol in saline will be injected followed by 1 mL of saline to avoid the deposition of phenol within the intervertebral disc material.

Timeline

• Start date: 2024-06-01
• Primary completion: 2025-06-01
• Completion: 2026-06-01
• First posted: 2024-04-30
• Last updated: 2024-05-02