NCT06391866

Neuroinflammation/Oxidative Stress/Cardiac Surgery

Assessing Neuroinflammation and Oxidative Stress After Cardiac Surgery: Unveiling Molecular Dynamics and Clinical Outcomes

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: EPC Education s.r.o. · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: —

Summary

The prospective observational study delves into the complex relationship between neuroinflammation and oxidative stress in post-cardiac surgery complications, focusing on postoperative cognitive dysfunction.

Detailed description

The prospective observational study meticulously examines the interplay between neuroinflammation and oxidative stress in the realm of post-cardiac surgery complications, specifically targeting postoperative cognitive dysfunction. Its primary objective is to comprehensively assess the sustained influence of these intricate processes on cognitive function and overall well-being, extending beyond the immediate aftermath of surgery. The research endeavors to probe deeply into the molecular mechanisms and clinical ramifications associated with neuroinflammation and oxidative stress, centering on their pivotal role in shaping the onset and trajectory of postoperative cognitive dysfunction.

Conditions

• Neuroinflammation

Interventions

Type	Name	Description
OTHER	extracorporeal circulation	extracorporeal circulation during cardiosurgical operation

Timeline

• Start date: 2024-04-30
• Primary completion: 2025-04-30
• Completion: 2025-12-31
• First posted: 2024-04-30
• Last updated: 2024-04-30

Locations

1 site across 1 country: Slovakia