NCT06390189

Inflammatory Resolution in Cardiometabolic Health and Disease

Inflammatory Resolution in Cardiometabolic Health and Disease - an Aarhus Based Cohort

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 240 (estimated)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The specific aim of this study is to determine molecular pathways that differentiate metabolically healthy vs unhealthy human phenotypes, and to investigate the therapeutic potential of pro-resolving lipids. Investigators will recruit volunteers that are metabolically healthy or unhealthy that fall within three BMI ranges: lean (18.-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (\>30.0 kg/m2). Investigators hypothesize that metabolically healthy individuals have a superior endogenous capacity to regulate an inflammatory/resolving response.

Conditions

• Inflammation
• Obesity
• Cardiovascular Diseases

Timeline

• Start date: 2024-05-07
• Primary completion: 2026-09-01
• Completion: 2028-09-01
• First posted: 2024-04-30
• Last updated: 2024-06-28

Locations

1 site across 1 country: Denmark