NCT06382935

Impact of Non-surgical Periodontal Treatment of miRNome

Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on miRNome in Gingival Tissues

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Catania · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid

Detailed description

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis. 60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise). Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

Conditions

• Periodontitis

Interventions

Type	Name	Description
OTHER	Probin Pocket Depth reduction	Probin Pocket Depth reduction in millimetres before and after treatment

Timeline

• Start date: 2024-04-20
• Primary completion: 2024-09-22
• Completion: 2024-10-15
• First posted: 2024-04-24
• Last updated: 2024-04-24

Locations

1 site across 1 country: Italy