NCT06381102

Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1

How Does the Length of Pulse Trains and Pulse Intervals Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	transcutaneous auricular vagus nerve stimulation 30/30	Transauricular vagus nerve stimulation (taVNS) is a simple technique in which small surface electrodes are placed over the skin of the ear that are thought to be innervated by the auricular branch of the vagus nerve (ABVN). Participants in this group will first receive taVNS with a 30 second on and 30 second off, for 1 hour, in-person.
DEVICE	transcutaneous auricular vagus nerve stimulation 10/10	Transauricular vagus nerve stimulation (taVNS) is a simple technique in which small surface electrodes are placed over the skin of the ear that are thought to be innervated by the auricular branch of the vagus nerve (ABVN). Participants in this group will first receive taVNS with a 10 second on and 10 second off, for 1 hour, in-person.

Timeline

• Start date: 2024-04-13
• Primary completion: 2024-10-01
• Completion: 2024-10-01
• First posted: 2024-04-24
• Last updated: 2025-08-24
• Results posted: 2025-08-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study