NCT06379438

Treatment of Aphtous Ulcers With Photodynamic Therapy

Treatment of Aphtous Ulcers With Photodynamic Therapy: A Randomised Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Yuzuncu Yil University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The search for methods that can shorten the treatment process of aphthous ulcers, the etiology of which is not fully understood, continues. The aim of this study was to determine whether photodynamic therapy (PDT) is a clinically effective alternative in the treatment of oral aphthous ulcers.

Detailed description

After sample size calculation, photodynamic therapy and control groups were formed with 15 patients with aphthous ulcer in each group. Laser therapy with indocyanine green was applied to the photodynamic therapy group on the day they were admitted to the clinic. No treatment was performed in the control group and only follow-up was performed. Lesion diameters, pain intensity and degree of improvement at the end of 1 week were recorded in all patients.

Conditions

• Oral Ulcer
• Aphthous Recurrent Ulcers

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Photodynamic therapy (indocyanine green+laser)	Photodynamic therapy with indocyanine green

Timeline

• Start date: 2018-03-05
• Primary completion: 2019-03-01
• Completion: 2019-03-08
• First posted: 2024-04-23
• Last updated: 2024-04-23

Locations

1 site across 1 country: Turkey (Türkiye)