NCT06379425

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries: A Randomized Controlled Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Northwell Health · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries. The investigators hypothesize that receipt of acetaminophen, celecoxib and gabapentin preoperatively versus acetaminophen alone will reduce the time to trial of void in patients undergoing same-day minor urogynecologic procedures.

Conditions

• Pain, Postoperative
• Postoperative Pain, Acute

Interventions

Type	Name	Description
DRUG	Acetaminophen	Will add additional medications celecoxib and gabapentin to acetaminophen preoperatively prior to patient surgery
DRUG	Celecoxib	Will add additional medications celecoxib and gabapentin to acetaminophen preoperatively prior to patient surgery
DRUG	Gabapentin	Will add additional medications celecoxib and gabapentin to acetaminophen preoperatively prior to patient surgery

Timeline

• Start date: 2024-03-01
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2024-04-23
• Last updated: 2025-05-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study