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Active Not RecruitingNCT06376084

Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC

Osimertinib With Chemotherapy as First-line Therapy for Patients With Locally Advanced or Metastatic Epidermal Growth Factor Receptor (EGFR) Mutation-positive Non-Small Cell Lung Cancer (NSCLC): A Multicentre, Observational Study (FOREFRONT)

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
532 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To estimate parameters related to clinical outcomes in a real-world seeting, including investigator reported PFS and OS .

Detailed description

The objectives of this study are to assess the effectiveness and safety of Osimertinib combined with chemotherapy in a real-world setting in patients with locally advanced or metastatic, EGFR mutation-positive NSCLC.

Conditions

Timeline

Start date
2024-07-23
Primary completion
2028-02-28
Completion
2028-02-28
First posted
2024-04-19
Last updated
2026-01-08

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06376084. Inclusion in this directory is not an endorsement.