NCT06372288

Theta Burst TMS for Treatment of Methamphetamine Use Disorder

Theta Burst Transcranial Magnetic Stimulation for the Treatment of Methamphetamine Use Disorder

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Carilion Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study is using Transcranial Magnetic Stimulation (TMS) to determine if interventional psychiatry treatment can help with the treatment of Methamphetamine Use Disorder. Individuals with Methamphetamine Use Disorder will receive 5 consecutive TMS treatment sessions based off of randomization. Participants will be randomized to one of two groups. TMS treatment arm or sham-TMS arm.

Detailed description

Patients who meet criteria for the study and who agree to participate in the research study will be randomized to an arm of the study by chance (like tossing a coin). The chance of receiving TMS or sham-TMS is equal. They will be enrolled in either the TMS or sham-TMS group (both groups involve 5 TMS or sham-TMS sessions). The study doctor and the participant will not know whether they are in the TMS or sham-TMS group. The purpose of this study is to determine if TMS is a potential treatment for methamphetamine use disorder. TMS is a non-invasive technique that uses magnetic pulses to temporarily stimulate specific brain areas in awake people (without the need for surgery, anesthetic, or other invasive procedures). This study will test whether a specific type of TMS (intermittent theta burst) over the forehead can produce a reduction in things that may prompt you to want to use methamphetamines.

Conditions

• Methamphetamine Abuse

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation	Transcranial Magnetic Stimulation (TMS using Intermittent theta burst stimulation (iTBS)
DEVICE	Sham Transcranial Magnetic Stimulation	Participants will not receive intermittent theta burst stimulation during the sham-TMS sessions

Timeline

• Start date: 2023-12-20
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2024-04-18
• Last updated: 2024-04-26

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study